| DATE | HOME | SCORE | AWAY | |||
|---|---|---|---|---|---|---|
| 17/09/2021 |  | CELTA DE VIGO | 1 - 2 | CÁDIZ |  | |
| 18/09/2021 |  | RAYO VALLECANO | 3 - 0 | GETAFE |  | |
| 18/09/2021 |  | ATLÉTICO MADRID | 0 - 0 | ATHLETIC BILBAO |  | |
| 18/09/2021 |  | ELCHE | 1 - 1 | LEVANTE |  | |
| 18/09/2021 |  | DEPORTIVO ALAVÉS | 0 - 2 | OSASUNA |  | |
| 19/09/2021 |  | MALLORCA | 0 - 0 | VILLARREAL |  | |
| 19/09/2021 |  | REAL SOCIEDAD | 0 - 0 | SEVILLA |  | |
| 19/09/2021 |  | REAL BETIS | 2 - 2 | ESPANYOL |  | |
| 19/09/2021 |  | VALENCIA | 1 - 2 | REAL MADRID |  | |
| 20/09/2021 |  | BARCELONA | 1 - 1 | GRANADA |  |
