| DATE | HOME | SCORE | AWAY | |||
|---|---|---|---|---|---|---|
| 17/12/2021 |  | CELTA DE VIGO | 3 - 1 | ESPANYOL |  | |
| 18/12/2021 |  | RAYO VALLECANO | 2 - 0 | DEPORTIVO ALAVÉS |  | |
| 18/12/2021 |  | REAL SOCIEDAD | 1 - 3 | VILLARREAL |  | |
| 18/12/2021 |  | BARCELONA | 3 - 2 | ELCHE |  | |
| 18/12/2021 |  | SEVILLA | 2 - 1 | ATLÉTICO MADRID |  | |
| 19/12/2021 |  | GRANADA | 4 - 1 | MALLORCA |  | |
| 19/12/2021 |  | ATHLETIC BILBAO | 3 - 2 | REAL BETIS |  | |
| 19/12/2021 |  | GETAFE | 1 - 0 | OSASUNA |  | |
| 19/12/2021 |  | REAL MADRID | 0 - 0 | CÁDIZ |  | |
| 20/12/2021 |  | LEVANTE | 3 - 4 | VALENCIA |  |
