| DATE | HOME | SCORE | AWAY | |||
|---|---|---|---|---|---|---|
| 25/09/2021 |  | SAINT-ÉTIENNE | 0 - 3 | OGC NICE |  | |
| 25/09/2021 |  | STRASBOURG | 1 - 2 | LOSC LILLE |  | |
| 25/09/2021 |  | OLYMPIQUE LYONNAIS | 1 - 1 | LORIENT |  | |
| 25/09/2021 |  | PARIS SAINT-GERMAIN | 2 - 0 | MONTPELLIER |  | |
| 26/09/2021 |  | BORDEAUX | 1 - 1 | STADE RENNAIS |  | |
| 26/09/2021 |  | STADE BRESTOIS | 1 - 2 | METZ |  | |
| 26/09/2021 |  | STADE DE REIMS | 3 - 1 | NANTES |  | |
| 26/09/2021 |  | TROYES | 1 - 1 | ANGERS |  | |
| 26/09/2021 |  | CLERMONT | 1 - 3 | MONACO |  | |
| 26/09/2021 |  | MARSEILLE | 2 - 3 | RC LENS |  |
