| DATE | HOME | SCORE | AWAY | |||
|---|---|---|---|---|---|---|
| 19/11/2021 |  | AUGSBURG | 2 - 1 | BAYERN MÜNCHEN |  | |
| 20/11/2021 |  | BORUSSIA DORTMUND | 2 - 1 | STUTTGART |  | |
| 20/11/2021 |  | LEVERKUSEN | 1 - 0 | BOCHUM |  | |
| 20/11/2021 |  | BORUSSIA M'GLADBACH | 4 - 0 | GREUTHER FÜRTH |  | |
| 20/11/2021 |  | HOFFENHEIM | 2 - 0 | RB LEIPZIG |  | |
| 20/11/2021 |  | ARMINIA BIELEFELD | 2 - 2 | WOLFSBURG |  | |
| 20/11/2021 |  | UNION BERLIN | 2 - 0 | HERTHA BERLIN |  | |
| 21/11/2021 |  | FREIBURG | 0 - 2 | EINTRACHT FRANKFURT |  | |
| 21/11/2021 |  | MAINZ 05 | 1 - 1 | KÖLN |  | |
 | |
