| DATE | HOME | SCORE | AWAY | GROUP | ||
|---|---|---|---|---|---|---|
| 21/10/2021 |  |
HJK HELSINKI | 0 - 5 | MACCABI TEL AVIV |  |
Group A |
| 21/10/2021 |  |
ALASHKERT | 0 - 3 | LASK LINZ |  |
Group A |
| 21/10/2021 |  |
ANORTHOSIS FAMAGUSTA | 2 - 2 | FLORA TALLINN |  |
Group B |
| 21/10/2021 |  |
BODØ/GLIMT | 6 - 1 | ROMA |  |
Group C |
| 21/10/2021 |  |
FEYENOORD | 3 - 1 | UNION BERLIN |  |
Group E |
| 21/10/2021 |  |
MACCABI HAIFA | 1 - 0 | SLAVIA PRAHA |  |
Group E |
| 21/10/2021 |  |
KØBENHAVN | 1 - 2 | PAOK THESSALONIKI |  |
Group F |
| 21/10/2021 |  |
VITESSE | 1 - 0 | TOTTENHAM HOTSPUR |  |
Group G |
| 21/10/2021 |  |
NŠ MURA | 1 - 2 | STADE RENNAIS |  |
Group G |
| 21/10/2021 |  |
QARABAĞ | 2 - 1 | KAIRAT ALMATY |  |
Group H |
| 21/10/2021 |  |
PARTIZAN BEOGRAD | 0 - 1 | GENT |  |
Group B |
| 21/10/2021 |  |
CSKA SOFIA | 0 - 1 | ZORYA LUHANSK |  |
Group C |
| 21/10/2021 |  |
CFR CLUJ | 0 - 1 | AZ ALKMAAR |  |
Group D |
| 21/10/2021 |  |
JABLONEC | 2 - 2 | RANDERS |  |
Group D |
| 21/10/2021 |  |
SLOVAN BRATISLAVA | 2 - 0 | LINCOLN RED IMPS |  |
Group F |
| 21/10/2021 |  |
BASEL | 3 - 1 | OMONIA NICOSIA |  |
Group H |
